Projects in HERO
HERO uses the term "Project" to define a collection of references used to support a report or document that the EPA is developing. The project pages listed below are further grouped based on the EPA programs they support. To learn more about navigating the references that are included on the project pages explore Using HERO.
Ammonia
Ammonia, Oral - Problem Formulation
tert-Amyl ethyl ether (TAEE) (919-94-8)
tert-Amyl methyl ether (TAME) (994-05-8)
Arsenic Hazard ID (7440-38-2)
Arsenic (Inorganic)
Arsenic MOA
Arsenic Susceptibility
Asbestos (1332-21-4)
BBP (Butyl benzyl phthalate)
Benzo(a)pyrene (BaP) (50-32-8)
Biphenyl (92-52-4)
n-Butanol (71-36-3)
tert-Butanol (75-65-0)
Chloroform 2018 Update (67-66-3)
Chloroform Combined (current) (67-66-3)
Chloroprene (126-99-8)
Chloroprene Request for Correction (RFC #21005 - 2021)
Chromium VI
Cobalt (7440-48-4)
DCM (Dichloromethane) (Final, 2011)
1,2-Dibromo-3-chloropropane (96-12-8)
Dibutyl Phthalate (DBP) (84-74-2)
Diethyl phthalate (DEP) (84-66-2)
Diisobutyl Phthalate (DIBP) Final (84-69-5)
Diisononyl Phthalate (DINP)
1,4-Dioxane - with inhalation update
Dioxin (2012 Project Page for Final Report) (1746-01-6)
ETBE (637-92-3)
Ethylbenzene (100-41-4)
Formaldehyde [archived] (50-00-0)
Hexabromocyclododecane (HBCD) (25637-99-4)
Hexachloroethane (HCE) (Final, 2011)
Inorganic Mercury Salts (2)
IRIS Formaldehyde (Inhalation) [Final 2024]
Libby Amphibole Asbestos (Draft, 2011)
Methanol (Non-Cancer) (67-56-1)
Methylmercury (22967-92-6)
Molybdenum (7439-98-7)
Naphthalene (91-20-3)
Nitrate/Nitrite
PCBs (1336-36-3)
Phthalates – Targeted Search for Epidemiological Studies
PM ISA
RDX (121-82-4)
SR Automation
Tetrachloroethylene (Perc) (Final, 2012)
Trichloroacetic acid (TCA) (Final, 2011)
Trichloroethylene (TCE) (Final, 2011)
Trimethylbenzenes (Interagency Science Discussion Draft)
Trimethylbenzenes (TMB)
Uranium
Uranium Toxicological Review (7440-61-1)
Vanadium Compounds - Problem Formulation
Vanadium Inhalation
Vanadium Pentoxide (Draft, 2011)
Ammonia, Oral - Problem Formulation
tert-Amyl ethyl ether (TAEE) (919-94-8)
tert-Amyl methyl ether (TAME) (994-05-8)
Arsenic Hazard ID (7440-38-2)
Arsenic (Inorganic)
Arsenic MOA
Arsenic Susceptibility
Asbestos (1332-21-4)
BBP (Butyl benzyl phthalate)
Benzo(a)pyrene (BaP) (50-32-8)
Biphenyl (92-52-4)
n-Butanol (71-36-3)
tert-Butanol (75-65-0)
Chloroform 2018 Update (67-66-3)
Chloroform Combined (current) (67-66-3)
Chloroprene (126-99-8)
Chloroprene Request for Correction (RFC #21005 - 2021)
Chromium VI
Cobalt (7440-48-4)
DCM (Dichloromethane) (Final, 2011)
1,2-Dibromo-3-chloropropane (96-12-8)
Dibutyl Phthalate (DBP) (84-74-2)
Diethyl phthalate (DEP) (84-66-2)
Diisobutyl Phthalate (DIBP) Final (84-69-5)
Diisononyl Phthalate (DINP)
1,4-Dioxane - with inhalation update
Dioxin (2012 Project Page for Final Report) (1746-01-6)
ETBE (637-92-3)
Ethylbenzene (100-41-4)
Formaldehyde [archived] (50-00-0)
Hexabromocyclododecane (HBCD) (25637-99-4)
Hexachloroethane (HCE) (Final, 2011)
Inorganic Mercury Salts (2)
IRIS Formaldehyde (Inhalation) [Final 2024]
Libby Amphibole Asbestos (Draft, 2011)
Methanol (Non-Cancer) (67-56-1)
Methylmercury (22967-92-6)
Molybdenum (7439-98-7)
Naphthalene (91-20-3)
Nitrate/Nitrite
PCBs (1336-36-3)
Phthalates – Targeted Search for Epidemiological Studies
PM ISA
RDX (121-82-4)
SR Automation
Tetrachloroethylene (Perc) (Final, 2012)
Trichloroacetic acid (TCA) (Final, 2011)
Trichloroethylene (TCE) (Final, 2011)
Trimethylbenzenes (Interagency Science Discussion Draft)
Trimethylbenzenes (TMB)
Uranium
Uranium Toxicological Review (7440-61-1)
Vanadium Compounds - Problem Formulation
Vanadium Inhalation
Vanadium Pentoxide (Draft, 2011)
ISA-CO (2010 Final Project Page)
ISA-Lead (2013 Final Project Page)
ISA - Lead (2024 Final Project Page)
ISA-NOx (2016)
ISA- NOx 2024
ISA NOxSOxPM Ecology (2018)
ISA NOxSOxPM Ecology (2020- Final Project Page)
ISA-Ozone (2013 Final Project Page)
ISA-Ozone (2020 Final Project Page)
ISA-PM (2009 Final Project Page)
ISA-PM (2019)
ISA – PM Supplement (2022)
ISA-SOx
LitSearch-NOx (2024)
Litsearch – PM ISA Supplement 2021
PM Provisional Assessment (2012 Project Page)
ISA-Lead (2013 Final Project Page)
ISA - Lead (2024 Final Project Page)
ISA-NOx (2016)
ISA- NOx 2024
ISA NOxSOxPM Ecology (2018)
ISA NOxSOxPM Ecology (2020- Final Project Page)
ISA-Ozone (2013 Final Project Page)
ISA-Ozone (2020 Final Project Page)
ISA-PM (2009 Final Project Page)
ISA-PM (2019)
ISA – PM Supplement (2022)
ISA-SOx
LitSearch-NOx (2024)
Litsearch – PM ISA Supplement 2021
PM Provisional Assessment (2012 Project Page)
Dibutyl sebacate (109-43-3)
Fatty Alcohols
Gluconates
Glycols
1,2-Hexanediol (6920-22-5)
Malonates
3-Methoxybutyl acetate (4435-53-4)
Propylene glycol ethers (88917-22-0 & 55934-93-5)
Sodium glucoheptonate (31138-65-5)
Squalane (111-01-3)
Fatty Alcohols
Gluconates
Glycols
1,2-Hexanediol (6920-22-5)
Malonates
3-Methoxybutyl acetate (4435-53-4)
Propylene glycol ethers (88917-22-0 & 55934-93-5)
Sodium glucoheptonate (31138-65-5)
Squalane (111-01-3)
Completed TSCA Risk Evaluations
OPPT_1,4-Dioxane_A. Summary
OPPT_1,4-Dioxane_B. Ecological Toxicology
OPPT_1,4-Dioxane_C. Engineering
OPPT_1,4-Dioxane_D. Exposure
OPPT_1,4-Dioxane_E. Fate
OPPT_1,4-Dioxane_F. Human Health
OPPT_1-Bromopropane (1-BP)_A. Summary
OPPT_1-Bromopropane (1-BP)_B. Ecological Toxicology
OPPT_1-Bromopropane (1-BP)_C. Engineering
OPPT_1-Bromopropane (1-BP)_D. Exposure
OPPT_1-Bromopropane (1-BP)_E. Fate
OPPT_1-Bromopropane (1-BP)_F. Human Health
OPPT_Asbestos, Part I: Chrysotile_A. Summary
OPPT_Asbestos, Part I: Chrysotile_B. Ecological Toxicology
OPPT_Asbestos, Part I: Chrysotile_C. Engineering
OPPT_Asbestos, Part I: Chrysotile_D. Exposure
OPPT_Asbestos, Part I: Chrysotile_E. Fate
OPPT_Asbestos, Part I: Chrysotile_F. Human Health
OPPT_Asbestos, Part I: Chrysotile_Supplemental Search
OPPT_Carbon Tetrachloride_A. Summary
OPPT_Carbon Tetrachloride_B. Ecological Toxicology
OPPT_Carbon Tetrachloride_C. Engineering
OPPT_Carbon Tetrachloride_D. Exposure
OPPT_Carbon Tetrachloride_E. Fate
OPPT_Carbon Tetrachloride_F. Human Health
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_A. Summary
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_B. Ecological Toxicology
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_C. Engineering
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_D. Exposure
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_E. Fate
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_F. Human Health
OPPT_Methylene Chloride_A. Summary
OPPT_Methylene Chloride_B. Ecological Toxicology
OPPT_Methylene Chloride_C. Engineering
OPPT_Methylene Chloride_D. Exposure
OPPT_Methylene Chloride_E. Fate
OPPT_Methylene Chloride_F. Human Health
OPPT_N-methylpyrrolidone (NMP)_A. Summary
OPPT_N-methylpyrrolidone (NMP)_B. Ecological Toxicology
OPPT_N-methylpyrrolidone (NMP)_C. Engineering
OPPT_N-methylpyrrolidone (NMP)_D. Exposure
OPPT_N-methylpyrrolidone (NMP)_E. Fate
OPPT_N-methylpyrrolidone (NMP)_F. Human Health
OPPT_Perchloroethylene (Perc)_A. Summary
OPPT_Perchloroethylene (Perc)_B. Ecological Toxicology
OPPT_Perchloroethylene (Perc)_C. Engineering
OPPT_Perchloroethylene (Perc)_D. Exposure
OPPT_Perchloroethylene (Perc)_E. Fate
OPPT_Perchloroethylene (Perc)_F. Human Health
OPPT_Pigment Violet 29 (PV29)_A. Summary
OPPT_Pigment Violet 29 (PV29)_B. Ecological Toxicology
OPPT_Pigment Violet 29 (PV29)_C. Engineering
OPPT_Pigment Violet 29 (PV29)_D. Exposure
OPPT_Pigment Violet 29 (PV29)_E. Fate
OPPT_Trichloroethylene (TCE)_A. Summary
OPPT_Trichloroethylene (TCE)_B. Ecological Toxicology
OPPT_Trichloroethylene (TCE)_C. Engineering
OPPT_Trichloroethylene (TCE)_D. Exposure
OPPT_Trichloroethylene (TCE)_E. Fate
OPPT_Trichloroethylene (TCE)_F. Human Health
OPPT_1,4-Dioxane_A. Summary
OPPT_1,4-Dioxane_B. Ecological Toxicology
OPPT_1,4-Dioxane_C. Engineering
OPPT_1,4-Dioxane_D. Exposure
OPPT_1,4-Dioxane_E. Fate
OPPT_1,4-Dioxane_F. Human Health
OPPT_1-Bromopropane (1-BP)_A. Summary
OPPT_1-Bromopropane (1-BP)_B. Ecological Toxicology
OPPT_1-Bromopropane (1-BP)_C. Engineering
OPPT_1-Bromopropane (1-BP)_D. Exposure
OPPT_1-Bromopropane (1-BP)_E. Fate
OPPT_1-Bromopropane (1-BP)_F. Human Health
OPPT_Asbestos, Part I: Chrysotile_A. Summary
OPPT_Asbestos, Part I: Chrysotile_B. Ecological Toxicology
OPPT_Asbestos, Part I: Chrysotile_C. Engineering
OPPT_Asbestos, Part I: Chrysotile_D. Exposure
OPPT_Asbestos, Part I: Chrysotile_E. Fate
OPPT_Asbestos, Part I: Chrysotile_F. Human Health
OPPT_Asbestos, Part I: Chrysotile_Supplemental Search
OPPT_Carbon Tetrachloride_A. Summary
OPPT_Carbon Tetrachloride_B. Ecological Toxicology
OPPT_Carbon Tetrachloride_C. Engineering
OPPT_Carbon Tetrachloride_D. Exposure
OPPT_Carbon Tetrachloride_E. Fate
OPPT_Carbon Tetrachloride_F. Human Health
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_A. Summary
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_B. Ecological Toxicology
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_C. Engineering
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_D. Exposure
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_E. Fate
OPPT_Cyclic Aliphatic Bromine Cluster (HBCD)_F. Human Health
OPPT_Methylene Chloride_A. Summary
OPPT_Methylene Chloride_B. Ecological Toxicology
OPPT_Methylene Chloride_C. Engineering
OPPT_Methylene Chloride_D. Exposure
OPPT_Methylene Chloride_E. Fate
OPPT_Methylene Chloride_F. Human Health
OPPT_N-methylpyrrolidone (NMP)_A. Summary
OPPT_N-methylpyrrolidone (NMP)_B. Ecological Toxicology
OPPT_N-methylpyrrolidone (NMP)_C. Engineering
OPPT_N-methylpyrrolidone (NMP)_D. Exposure
OPPT_N-methylpyrrolidone (NMP)_E. Fate
OPPT_N-methylpyrrolidone (NMP)_F. Human Health
OPPT_Perchloroethylene (Perc)_A. Summary
OPPT_Perchloroethylene (Perc)_B. Ecological Toxicology
OPPT_Perchloroethylene (Perc)_C. Engineering
OPPT_Perchloroethylene (Perc)_D. Exposure
OPPT_Perchloroethylene (Perc)_E. Fate
OPPT_Perchloroethylene (Perc)_F. Human Health
OPPT_Pigment Violet 29 (PV29)_A. Summary
OPPT_Pigment Violet 29 (PV29)_B. Ecological Toxicology
OPPT_Pigment Violet 29 (PV29)_C. Engineering
OPPT_Pigment Violet 29 (PV29)_D. Exposure
OPPT_Pigment Violet 29 (PV29)_E. Fate
OPPT_Trichloroethylene (TCE)_A. Summary
OPPT_Trichloroethylene (TCE)_B. Ecological Toxicology
OPPT_Trichloroethylene (TCE)_C. Engineering
OPPT_Trichloroethylene (TCE)_D. Exposure
OPPT_Trichloroethylene (TCE)_E. Fate
OPPT_Trichloroethylene (TCE)_F. Human Health
5:3 acid (914637-49-3)
6:2/8:2 diPAP (943913-15-3)
6:2 diPAP (57677-95-9)
6:2 Fluorotelomer sulfonic acid (27619-97-2)
6:2 monoPAP (57678-01-0)
8:2 diPAP (678-41-1)
8:2 monoPAP (57678-03-2)
Additional PFAS (formerly XAgency)
ADONA (919005-14-4)
Expanded PFAS SEM (formerly PFAS 430)
FtOH 6:2 (647-42-7)
FtOH 8:2 (678-39-7)
FtS 8:2 (39108-34-4)
GenX Chemicals (CASRN 13252-13-6 and CASRN 62037-80-3)
Nafion (311-20-9)
NEtFOSAA (2991-50-6)
NMeFOSAA (2355-31-9)
^Per- and Polyfluoroalkyl Substances (PFAS)
PFAS 150
PFAS Universe
PFBA (375-22-4)
PFBS (375-73-5)
PFDA (335-76-2)
PFDS (335-77-3)
PFHpA (375-85-9)
PFHpS (375-92-8)
PFHxA (307-24-4)
PFHxS (355-46-4)
PFNA (375-95-1)
PFNS (68259-12-1)
PFOA (335-67-1) and PFOS (1763-23-1)
PFOA and PFOS OW MCLG Approaches
PFOSA (754-91-6)
PFPeA (2706-90-3)
PFPeS (2706-91-4)
PFUnA (2058-94-8)
R5-MI STSC Request
6:2/8:2 diPAP (943913-15-3)
6:2 diPAP (57677-95-9)
6:2 Fluorotelomer sulfonic acid (27619-97-2)
6:2 monoPAP (57678-01-0)
8:2 diPAP (678-41-1)
8:2 monoPAP (57678-03-2)
Additional PFAS (formerly XAgency)
ADONA (919005-14-4)
Expanded PFAS SEM (formerly PFAS 430)
FtOH 6:2 (647-42-7)
FtOH 8:2 (678-39-7)
FtS 8:2 (39108-34-4)
GenX Chemicals (CASRN 13252-13-6 and CASRN 62037-80-3)
Nafion (311-20-9)
NEtFOSAA (2991-50-6)
NMeFOSAA (2355-31-9)
^Per- and Polyfluoroalkyl Substances (PFAS)
PFAS 150
PFAS Universe
PFBA (375-22-4)
PFBS (375-73-5)
PFDA (335-76-2)
PFDS (335-77-3)
PFHpA (375-85-9)
PFHpS (375-92-8)
PFHxA (307-24-4)
PFHxS (355-46-4)
PFNA (375-95-1)
PFNS (68259-12-1)
PFOA (335-67-1) and PFOS (1763-23-1)
PFOA and PFOS OW MCLG Approaches
PFOSA (754-91-6)
PFPeA (2706-90-3)
PFPeS (2706-91-4)
PFUnA (2058-94-8)
R5-MI STSC Request
Alaska Waste and Health Impacts
Atrazine SAP 2023
Exposure Factors Handbook (Post 2011)
Exposure Manuscripts
Harmful Algal Blooms- Health Effects
Hypoxia Task Force literature reviews
Justice, Equity, Diversity, and Inclusion (JEDI) Resources
Mouse Lung Tumor Workshop 2014
MSA-Multipollutant Exposure Metric Review
Nanoscale Carbon
Nanoscale Silver
Naphthalene (2021 Evidence mapping publication)
Nutrient Stressors and Biological Responses
Perfluoro-3-Methoxypropanoic Acid
Probabilistic Methods (Dose Response Panel)
Project 9 – Soil and Dust Ingestion
Public Metadata
Ramazzini Institute
Third Biofuels Report to Congress
WFLC - CAIF Report
Yale PFAS Liver study
Atrazine SAP 2023
Exposure Factors Handbook (Post 2011)
Exposure Manuscripts
Harmful Algal Blooms- Health Effects
Hypoxia Task Force literature reviews
Justice, Equity, Diversity, and Inclusion (JEDI) Resources
Mouse Lung Tumor Workshop 2014
MSA-Multipollutant Exposure Metric Review
Nanoscale Carbon
Nanoscale Silver
Naphthalene (2021 Evidence mapping publication)
Nutrient Stressors and Biological Responses
Perfluoro-3-Methoxypropanoic Acid
Probabilistic Methods (Dose Response Panel)
Project 9 – Soil and Dust Ingestion
Public Metadata
Ramazzini Institute
Third Biofuels Report to Congress
WFLC - CAIF Report
Yale PFAS Liver study