Potential mechanisms of adverse pulmonary and cardiovascular effects of particulate air pollution (PM10) | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

1057753

Reference Type

Journal Article

Title

Potential mechanisms of adverse pulmonary and cardiovascular effects of particulate air pollution (PM10)

Author(s)

Donaldson, K; Macnee, W

Year

2001

Is Peer Reviewed?

Yes

Journal

International Journal of Hygiene and Environmental Health
ISSN: 1438-4639
EISSN: 1618-131X

Volume

203

Issue

5-6

Page Numbers

411-415

PMID

11556145

DOI

10.1078/1438-4639-00059

Web of Science Id

WOS:000170612900005

URL

http://linkinghub.elsevier.com/retrieve/pii/S143846390470053X
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Abstract

PM10 is the international convention for measuring
environmental particulate air pollution. Increases in PM10 have been linked to exacerbations of
airways disease and deaths from respiratory and cardiovascular causes. PM10 is a complex and
variable mixture but toxicological data suggests that ultrafine particles, transition metals and
endotoxins are the most likely components to mediate adverse health effects. Potential mechanisms
for the local and systemic adverse effects of PM10 are discussed.

Keywords

PM10; air pollution; ultrafine particles; transition metals; endotoxin; cardiovascular