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1316836 
Technical Report 
Urea Formaldehyde Foam Insulation (UFFI) 
Harrison, JR; Campbell, JS 
1983 
Harrison, JR; Campbell, JS 
NIOSH/00154851 
38 
10 
1227-1229 
Problems involving the use of urea-formaldehyde (9011056) foam insulation (UFFI) are explored. Animal data is reviewed for comparison. Hazards of formaldehyde (50000) exposure in humans include carcinogenicity, primarily squamous metaplasia developing into squamous cell carcinoma with polyploid adenomas of the nasal cavities; sensitization and irritation in which challenge provokes an asthmatic response, allergic eczematous contact dermatitis, or eye irritation; possibility of physical trauma; possibility of electrical circuitry failure due to corrosion; and stress from coping with unsuccessful removal of insulation. UFFI releases free formaldehyde that passes through gypsum wall board and other materials not containing a vapor barrier. Usual ambient concentrations range 0.005 to 0.06 part per million. Exposure to concentrations above 1.0 part per million produces effects in most individuals. Production of changes in sister chromatid exchanges has been demonstrated, although animal studies show no excess mortality at usual concentrations. Formaldehyde may produce tumors at other than respiratory sites and may be synergistic with other substances. 
DCN-142163; Insulation materials; Materials testing; Exposure levels; Carcinogenicity; Nasal disorders; Genetic disorders; Mutagenesis; Physiological response; Biological effects; Sensitization; Pulmonary system disorders 
IRIS
• Formaldehyde
     Immune Section
          Reviews and reports
     Inflammation/Reactive Oxygen Species
          Toxline
          Screened by Title/Abstract
               Not Primary Study: Review, Commentary, Abstract, Policy, Current Practice, Workplace Assessment
     Retroactive RIS import
          2013
               HERO Formaldehyde Immune Section 20Mar2013
          2014
               HERO_Formaldehyde_InflammationReactiveOxygenSpecies_pid_31_uid_5713Sorting091214
               HERO_Formaldehyde_InflammationReactiveOxygenSpecies_pid_31_uid_5713
                    Screened (Title/Abstract)
                         Not Primary Study: Review, Commentary, Abstract, Policy, Current Practice, Workplace Assessment, etc
               Immune_HERO_allyr