US EPA

1317736 

Journal Article 

Contact Sensitization to Organosilane Solution in Glass Filament Production 

Heino, T; Haapa, K; Manelius, F 

1996 

Yes 

Contact Dermatitis
ISSN: 0105-1873
EISSN: 1600-0536 

NIOSH/00230815 

34 

4 

Of 61 workers in a glass fiber factory who were exposed to a new organosilane coating mixture, eight developed an itchy erythematous papular dermatitis. The dermatitis developed on parts of the body that were in direct contact with coating solutions. The coating mixture was Dow Corning Z-6032 silane. Six other coating solutions were also in use at the facility. When patch tested, six of the eight workers with the occupational contact dermatitis were positive to one or more substances; five reacted to epoxy resin, two reacted to formaldehyde (50000), and four reacted to an organosilane solution. The authors conclude that organosilane solutions may be an important source of contact sensitization in glass fiber workers; however, the actual allergen within the solution remains unknown. 

DCN-231241; Skin disorders; Contact dermatitis; Allergic dermatitis; Occupational exposure; Humans; Fiberglass industry; Skin exposure