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Citation
Tags
HERO ID
1401399
Reference Type
Journal Article
Subtype
Review
Title
[Endocrine disruptors and obesity: obesogens]
Author(s)
García-Mayor, RV; Larrañaga Vidal, A; Docet Caamaño, MF; Lafuente Giménez, A
Year
2012
Is Peer Reviewed?
0
Journal
Endocrinologia y Nutricion
ISSN:
1575-0922
EISSN:
1579-2021
Volume
59
Issue
4
Page Numbers
261-267
Language
Spanish
PMID
22300604
DOI
10.1016/j.endonu.2011.11.008
Abstract
Incidence and prevalence of owerweight and obesity have greatly increased over the past three decades in almost all countries around the world. This phenomenon is not easily explained by lifestyle changes in populations with very different initial habits. This has led to consider the influence of other factors, the so-called endocrine disruptors, and more specifically obesogens. This study reviewed the available evidence about polluting chemical substances which may potentially be obesogens in humans: DES, genistein, bisphenol A, organotins (TBT, TPT), and phthalates. The first three groups of substances mainly act upon estrogen receptors, while organotins and phthalates activate PPARγ. It was concluded that evidence exists of the obesogenic effect of these chemical substances in tissues and experimental animals, but few data are available in humans.
Tags
IRIS
•
Phthalates – Targeted Search for Epidemiological Studies
Source – all searches
Pubmed
Toxnet
Excluded
Source – no date limit through June 2013 (Private)
Pubmed
ToxNet
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