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Citation
Tags
HERO ID
1411137
Reference Type
Journal Article
Subtype
Abstract
Title
[Toxicity of BPA and TBBPA to Daphnia magna and zebrafish Brachydanio rerio]
Author(s)
Liu, HL; Liu, XH; Wang, XY; Wang, XR; Yu, HX
Year
2007
Is Peer Reviewed?
Yes
Journal
Huanjing Kexue / Chinese Journal of Environmental Science
ISSN:
0250-3301
Volume
28
Issue
8
Page Numbers
1784-1787
Language
Chinese
PMID
17926411
URL
https://www.scopus.com/inward/record.uri?eid=2-s2.0-34548361477&partnerID=40&md5=17674dfb41e5b5c2bdb60ae94cd3c044
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Abstract
Acute toxicity of BPA and TBBPA to Daphnia magna, zebrafish (Brachydanio rerio) and development effects of zebrafish embryo and zebrafish. The tested chemicals remarkably restrained the were studied, and safety assessment was also made to Daphnia magna mobilization of Daphnia magna, which may cause them death. 48 h EC50 values for D. magna were 8.91 and 0.69 mg x L(-1) respectively. In addition, the chemicals showed the toxicity effects on zebrafish, and 96 h LC50 values were 9.06 and 1.78 mg x L(-1) respectively. BPA and TBBPA remarkably retarded the development of zebrafish embryos, which may cause embryo abnormality and death. And the most sensitive toxicological endpoints to BPA and TBBPA were found, 72 h EC50 (malformation and embryo do not hatch) values were 2.90 and 0.14 mg x L(-1) respectively. The results showed that zebrafish embryo should be the most sensitive to the tested chemicals. The results indicated that BPA and TBBPA were the pollutants with high toxicity, in which TBBPA had the higher toxicity. BPA is a potential teratogen to zebrafish embryos, while TBBPA restrains embryo from hatch.
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