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1525736 
Journal Article 
Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation 
Belanger, M; Allaman, I; Magistretti, PJ 
2011 
Yes 
Cell Metabolism
ISSN: 1550-4131 
14 
6 
724-738 
22152301 
WOS:000298122400006 
The energy requirements of the brain are very high, and
tight regulatory mechanisms operate to ensure adequate spatial and temporal delivery of energy
substrates in register with neuronal activity. Astrocytes a type of glial cell have emerged as
active players in brain energy delivery, production, utilization, and storage. Our understanding
of neuroenergetics is rapidly evolving from a ""neurocentric"" view to a more integrated picture
involving an intense cooperativity between astrocytes and neurons. This review focuses on the
cellular aspects of brain energy metabolism, with a particular emphasis on the metabolic
interactions between neurons and astrocytes.