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1541780 
Journal Article 
Linking immunity to atherosclerosis: Implications for vascular pharmacology - A tribute to Goran K. Hansson 
Geng, YJ; Jonasson, L 
2012 
1 
Vascular Pharmacology
ISSN: 1537-1891
EISSN: 0306-3623 
56 
1-2 
29-33 
22120836 
WOS:000300121400005 
For the past decade, we have deepened our understanding of
the pathogenesis of atherosclerosis, a chronic arterial disease that causes cardiac and cerebral
infarction and peripheral vascular disorders. Because of this extended understanding, more
effective strategies for prevention and treatment of this disease are emerging. One of the
fundamental mechanisms that lead to progress or regression in atherosclerosis, thus influencing
its life-threatening complications, occurs through functional changes in vascular immunity and
inflammation. This review briefly summarizes the discoveries in basic and translational sciences
in this area and recent advances in clinical medicine against atherosclerotic vascular diseases.
(C) 2011 Elsevier Inc. All rights reserved. 
Atherosclerosis; Immunity; Inflammation; Macrophages; Lymphocytes; Antibody; Immunotherapy