Health & Environmental Research Online (HERO)


Print Feedback Export to File
1559284 
Journal Article 
Biological Activities of Freshwater Algae, Spirogyra singularis Nordstedt 
Nabavi, SF; Nabavi, SM; Ebrahimzadeh, M; Jafari, N; Yazdanpanah, S 
2013 
Yes 
Journal of Aquatic Food Product Technology
ISSN: 1049-8850
EISSN: 1547-0636 
22 
1 
58-65 
WOS:000313414600007 
Spirogyra is commonly found as accessible algae in
freshwater areas all over the world. Some medical uses have been reported from this genus.
Biological activities of Spirogyra singularis were investigated employing eight in vitro assays.
The extract showed different antioxidant activity. IC50 for DPPH radical-scavenging was 4.71 +/-
0.11 mu g mL-1. The extract showed very strong nitric oxide-scavenging activity with IC50 = 77.3
+/- 2.07 mu g mL-1, but its Fe2+ chelating ability was weak. The extract also exhibited high
antioxidant activity in hemoglobin-induced linoleic acid peroxidation tests and scavenging of
hydrogen peroxide. The extract also showed good antihemolytic activity. The total amount of
phenolic content in the extract was determined as gallic acid equivalents, and total flavonoid
content was calculated as quercetin equivalents. Biological activities may be attributed, at
least in part, to the presence of phenol and flavonoid contents in the extract. 
antioxidant activity; antihemolytic activity; green algae; radical scavenging; Spirogyra singularis