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1568581 
Journal Article 
The Mouse Retina as an Angiogenesis Model 
Stahl, A; Connor, K; Sapieha, P; Chen, J; Dennison, RJ; Krah, NM; Seaward, MR; Willett, KL; Aderman, CM; Guerin, KI; Hua, J; Lofqvist, C; Hellstrom, Ann; Smith, LEH 
2010 
Yes 
Investigative Ophthalmology and Visual Science
ISSN: 0146-0404
EISSN: 1552-5783 
51 
2813-2826 
The mouse retina has been used extensively over the past
decades to study both physiologic and pathologic angiogenesis. Over time, various mouse retina
models have evolved into well-characterized and robust tools for in vivo angiogenesis research.
This article is a review of the angiogenic development of the mouse retina and a discussion of
some of the most widely used vascular disease models. From the multitude of studies performed in
the mouse retina, a selection of representative works is discussed in more detail regarding their
role in advancing the understanding of both the ocular and general mechanisms of angiogenesis.
(Invest Ophthalmol Vis Sci. 2010; 51: 2813-2826) DOI:10.1167/iovs.10-5176