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1569643 
Book/Book Chapter 
Effects of Moderate Short-Term Intermittent Aerobic Exercise on Arterial Stiffness - Evaluation by Stiffness Parameter and Pressure-Strain Elastic Modulus- 
Tanaka, M; Sugawara, M; Niki, K; Kodera, H; Izumi, T 
2012 
IFMBE Proceedings 
37 
427-429 
WOS:000310938200111 
Background and purpose: Aerobic exercise decreases arterial stiffness. However, the direct measurements of alterations in pulsatile arterial diameter change have been poorly reported. Using echo-tracking method, we measured pulsatile changes in carotid arterial diameter, and evaluated the alteration in arterial stiffness effected by aerobic exercise. Methods: Ten healthy young volunteers (7 men, mean age 21.2 +/- 1.3 years) were studied before and 8 weeks after moderate intermittent (two or three times a week) aerobic exercise. Pulsatile changes in carotid arterial diameter were continuously recorded in M-mode 2 cm proximal to the carotid sinus from a long axis view. Systolic and diastolic pressures (Ps and Pd) were measured with a cuff-type manometer applied to the upper arm. Stiffness parameter (beta) was defined as In (Ps/Pd) / [(Ds - Dd) / Dd], where In is the natural logarithm, Ds and Dd are the systolic and diastolic diameter values. Pressure-strain elastic modulus (Ep) was defined as (Ps - Pd) / [(Ds - Dd) / Dd]. Results: As expected, beta and Ep decreased significantly ( beta: p < 0.02, Ep: p < 0.05). Conclusion: Even short term moderate intermittent exercise reduces carotid arterial stiffness in young adults. 
stiffness parameter; pressure -strain elastic modulus; exercise