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1575939 
Journal Article 
The plerotic effect of Yunnan Baiyao on renal injury after extracorporeal shock wave lithotripsy 
Yu, H; Rao, D; Duan, P 
2012 
6 
18 
1363-1366 
WOS:000307941000005 
The objective of this study was to explore the protective
effect of Yunnan Baiyao, a traditional Chinese herbal remedy, on renal function after
extracorporeal shock wave lithotripsy (ESWL). 55 patients with renal pelvic stones were
randomized to two groups: The control group (n = 25), where the patients were administered with
Paishi Chongji (a traditional Chinese herbal granule for removing stones) after ESWL; and the
study group (n = 30), where the patients were administered with Paishi Chongji and Yunnan Baiyao
after ESWL. Urine microproteins and peripheral venous malondialdehyde (MDA), superoxide dismutase
(SOD), endothelin-1 (ET-1) and nitric oxide (NO) were determined before ESWL, and at 24, 72 h and
one week after ESWL. Urine, albumin (ALB), immunoglobulin (IgG) and beta-2-microglobulin (beta 2
-MG) levels increased significantly, and urine THP decreased significantly after ESWL. Peripheral
ET-1 and MDA at 24 and 72 h after ESWL were significantly lower, while peripheral SOD and NO were
significantly higher in the study group than those in the control group (both P < 0.05). In
conclusion, Yunnan Baiyao has a definite plerotic effect on renal injury after ESWL and could be
spread widely for clinical use. 
Yunnan Baiyao; renal injury; extracorporeal shock wave lithotripsy (ESWL)