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1586431 
Journal Article 
Adsorption of bovine serum albumin onto titanium dioxide nanotube arrays 
Shi, Jie; Feng, Bo; Lu, X; Weng, Jie 
2012 
103 
7 
889-896 
WOS:000307328700013 
Titanium dioxide nanotube arrays on titanium were fabricated
via anodic oxidation and heat treatment. The diameters of nanotubes ranged from 20 to 200 nm, and
the lengths were 500 and 1000 nm. The adsorption behavior of bovine serum albumin onto the
nanotube arrays was investigated. Surface characterization for samples was carried out using
scanning electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and X-
ray photoelectron spectroscopy. Adsorbance of bovine serum albumin was detected with an
ultraviolet spectrophotometer. The results showed that the nanotube arrays on titanium surfaces
significantly enhanced bovine serum albumin adsorption. The nanotube arrays with larger diameter
could adsorb more bovine serum albumin, but longer nanotubes showed less adsorbance than shorter
nanotubes. In the present work, the nanotube arrays with 160-200 nm diameter, the largest
diameter, showed the highest adsorption ability, and the maximum adsorption capacity q(m) was
31.40 mg . cm(-2). In addition, the adsorbance of bovine serum albumin increased with increase of
initial bovine serum albumin concentrations, and a saturation value was achieved at the initial
bovine serum albumin concentration of 2.0 mg . ml(-1). 
Titanium dioxide nanotube arrays; Nanotube diameter; Nanotube length; Bovine serum albumin; Adsorption