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HERO ID
1594995
Reference Type
Journal Article
Title
Synthesis of Biologically Active Carbazole Alkaloids Using Selective Transition-metal-catalyzed Coupling Reactions
Author(s)
Knoelker, HJ
Year
2009
Is Peer Reviewed?
Yes
Journal
Chemistry Letters
ISSN:
0366-7022
EISSN:
1348-0715
Volume
38
Issue
1
Page Numbers
8-13
DOI
10.1246/cl.2009.8
Web of Science Id
WOS:000263629500002
Abstract
Highly convergent syntheses of substituted carbazoles are
most conveniently achieved using organometallic chemistry. Construction of the carbazole
framework via the iron-mediated route proceeds by a sequence of C-C and C-N bond formation. In
the highly efficient palladium-catalyzed route the C-N bond is formed first followed by
generation of the C-C bond. This article highlights some recent developments and applications to
the total synthesis of biologically active carbazole alkaloids.
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