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1596177 
Journal Article 
Review 
Development of New Catalytic Reactions Based on Activation of Hydrocarbon Functional Groups by Lewis Acids 
Tsuchimoto, T 
2011 
1 
Yuki Gosei Kagaku Kyokaishi
ISSN: 0037-9980 
SOC SYNTHETIC ORGANIC CHEM JPN 
TOKYO 
69 
8 
889-903 
WOS:000294079000004 
Over a long period of time, in the field of synthetic
organic chemistry, Lewis acids have been used mainly as activators for heteroatom-containing
functional groups such as carbonyls, imines and halides, in contrast to the traditional approach
utilizing such Lewis acid chemistry, we have been focusing on developing new catalytic reactions
on the basis of activation of hydrocarbon functional groups by Lewis acids. In order to activate
effectively the hydrocarbon functional groups classified into C C, C = C, C - C and C - H, an
appropriate choice of a Lewis acid catalyst is a crucial aspect. Herein, I disclose our recent
achievements based on the Lewis acid-activated hydrocarbon functional groups. 
indium; metal triflate; Lewis acid; alkyne; carbazole; heteroarene; pyrrole; furan; thiophene; nucleophilic aromatic substitution