A mild and practical synthesis of biphenyl compounds | Health & Environmental Research Online (HERO)

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Citation
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HERO ID

1611014

Reference Type

Journal Article

Title

A mild and practical synthesis of biphenyl compounds

Author(s)

Liang, S; Cao, X; Yan, X; Chen, L

Year

2012

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Journal

Journal of Chemical Research
ISSN: 1747-5198
EISSN: 2047-6507

Volume

Issue

Page Numbers

555-556

Language

English

DOI

10.3184/174751912X13419099572319

Web of Science Id

WOS:000309399900017

URL

http://://WOS:000309399900017
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Abstract

A mild and practical synthetic route for biphenyls is established. Isopropyl nitrite was prepared from sodium nitrite, isopropanol and hydrochloric acid. The biphenyl compounds were obtained from the diazotisation of aniline derivatives with the generated isopropyl nitrite and the coupling reaction with benzene derivatives in the presence of CuCl as a catalyst in good yields.

Keywords

biphenyls; aniline derivative; isopropyl nitrite; diazotisation