Metabolism of N-nitroso-2-oxopropylpropylamine by rat liver: formation of products resulting from both oxidation and reduction | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

1616277

Reference Type

Journal Article

Title

Metabolism of N-nitroso-2-oxopropylpropylamine by rat liver: formation of products resulting from both oxidation and reduction

Author(s)

Park, KK; Archer, MC

Year

1978

Is Peer Reviewed?

Yes

Journal

Cancer Biochemistry Biophysics
ISSN: 0305-7232

Volume

Issue

Page Numbers

37-40

Language

English

PMID

552897

Abstract

Metabolism of N-nitroso-2-oxopropylpropylamine (NOPPA) with either a microsomal preparation or the soluble enzyme fraction from rat liver yielded N-nitroso-2-hydroxypropylpropylamine (NHPPA). We have also identified and quantified propionaldehyde, n-propanol and isopropanol following incubation of NOPPA with the microsomal fraction.