Health & Environmental Research Online (HERO)


Print Feedback Export to File
1666007 
Book/Book Chapter 
Endogenous formation of N-nitroso compounds: a current perspective 
Tannenbaum, SR 
1987 
International Agency for Research on Cancer 
Lyon, France 
The Relevance of N-Nitroso Compounds to Human Cancer: Exposures and Mechanisms 
292-296 
English 
3679388 
Exposure of people to nitrosating agents occurs through multiple pathways, ranging from nitrogen dioxide reactions in the lung to acid-catalysed nitrosation in the stomach to nitrosation mediated by macrophages or bacteria. The use of N-nitrosoproline (NPRO) as an index of endogenous nitrosation has proved to be especially valuable for some of these pathways but may not be universally indicative. Since the development of the NPRO test by Ohshima and Bartsch in 1981, several forms of the test have been used for different purposes. This paper examines some of the issues related to endogenous nitrosation and NPRO and attempts to view the immediate future. 
Bartsch, H; O'Neill, IK; Schulte-Hermann, R 
IARC scientific publications 
978-92-832-1184-6 
IRIS
• Nitrate/Nitrite
     ATSDR literature
     Supplemental LitSearch Update 1600-2015
          PubMed
          New to project