US EPA

1684931 

Journal Article 

Group separation of organic nitrates on a new nitric acid ester NP-LC stationary phase 

Kastler, J; Dubourg, V; Deisenhofer, R; Ballschmiter, K 

1998 

Yes 

Chromatographia
ISSN: 0009-5893
EISSN: 1612-1112 

47 

3-4 

157-163 

WOS:000072233100005 

http://link.springer.com/10.1007/BF02466575
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The synthesis of a nitric acid ester NP-LC stationary phase (organonitrate phase), by nitrating a commercial polyol phase (Serva, Polyol Si 100, 5 mu m) with mixed sulfuric- and nitric acid, is reported. The nitric acid ester bond is quite stable towards hydrolysis. To examine its possible use as a stationary phase for the group separation of alkyl nitrates, several bifunctional polar alkyl nitrates (di-nitrates, hydroxy-nitrates, keto-nitrates) have been synthesized. In order to simplify their names a new abbreviating nomenclature for multifunctional organic nitrates is presented. With our new stationary phase it is possible to separate mono-, di-, and hydroxy-nitrates as groups completely, a major advantage in sample preparation in the chemistry of smog formation. However a co-elution of di- and keto-nitrates is observed. A distinction of the latter two organonitrate groups is possible by gas chromatography-mass spectrometric detection (MSD). Apart from the fragment ion NO2+ (m/z = 46 amu), which is nearly specific for alkyl nitrates, aliphatic di- and keto-nitrates show different characteristic fragment ions. 

column liquid chromatography; nitric acid ester phase; alkyl nitrates; group separation