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1761351 
Journal Article 
Effect of soft laser and bioactive glass on bone regeneration in the treatment of infra-bony defects (a clinical study) 
Aboelsaad, NS; Soory, M; Gadalla, LMA; Ragab, LI; Dunne, S; Zalata, KR; Louca, C 
2009 
1 
Lasers in Medical Science
ISSN: 0268-8921
EISSN: 1435-604X 
24 
3 
387-395 
18581160 
WOS:000265499300013 
This study aimed to investigate the influence of low-power
830 nm gallium-aluminium-arsenide (GaAlAs) laser [continuous wave (CW) 40 mW and fluence 4 J/cm
(2), with total energy density of 16 J/cm(2)] on the healing of human infra-bony defects treated
with bioactive glass graft material. Twenty patients with chronic periodontitis and bilateral
infra-bony defects were included. Using a split mouth design, we treated 20 defects with
bioactive glass plus laser irradiation during surgical procedures and on days 3, 5, 7
postoperatively; 20 contra-lateral defects were treated with bioactive glass only. Clinical
probing pocket depths, clinical attachment levels and standardized periapical radiographs were
recorded at baseline and at 3 months and 6 months postoperatively. At 3 months there was a
statistically significant difference between the laser and non-laser sites in the parameters
investigated. However, at 6 months, no difference was observed. Our results have confirmed the
positive effect of soft laser in accelerating periodontal wound healing. 
Bioactive glass; Bone graft; Bone healing; Diode laser