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1762589 
Journal Article 
A 3-Dimensional Nanobiosensor Based on an Anodic Aluminum Oxide Template 
Wang, GJ; Lin, YD 
2009 
217-220 
WOS:000273330500060 
In this paper, we propose a high sensitive nanobiosensor
based on a 3D sensing element that has uniformly deposited gold nanoparticles. The barrier layer
of an anodic aluminum oxide (AAO) film was used as the template; a reducing agent and
stabilizer-free method where the electrochemical deposition was utilized to synthesize uniformly
distributed gold nanoparticles on the surface of the barrier layer; the distribution density and
size of the nanoparticles can be well controlled by the potential applied during electrochemical
deposition.; following, receptors or antibodies with respect to a certain biomarker are attached
to the gold nanoparticles. 
nanobiosensor; electrochemical deposition; anodic aluminum oxide template