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1808715 
Journal Article 
Toxic amines and alkaloids from Acacia rigidula 
Clement, BA; Goff, CM; Forbes T, DA 
1998 
1 
Phytochemistry
ISSN: 0031-9422
EISSN: 1873-3700 
BIOSIS/99/00990 
OXFORD 
OXFORD 
1377-1380 
eng 
BIOSIS COPYRIGHT: BIOL ABS. Acacia rigidula Benth., blackbrush, is a shrub found growing on rocky ridges in west and southwest Texas and northern Mexico. Consumption of blackbrush and a related species guajillo, Acacia berlandieri Benth., has been associated with a locomotor ataxia known as "limber leg". In an effort to identify the mechanism of this toxicity, blackbrush was subjected to rigorous chemical analysis. In addition to the four previously detected amines, N-methyl-beta-phenethylamine, tyramine, N-methyltyramine, and hordenine, 40 other alkaloids and amines were isolated and identified by GC-MS. These alkaloids and amines included nicotine, N,N-dimethyltryptamine, mescaline, several tetrahydroisoquinoline alkaloids, and four amphetamines. A significant increase in the number and relative quantities of these compounds was observed in late season foliage. 
Biochemical Studies-General; Biophysics-Molecular Properties and Macromolecules; Toxicology-General; Plant Physiology; Leguminosae