US EPA

188 

Journal Article 

Asbestos exposure, smoking, and neoplasia 

Selikoff, IJ; Hammond, EC; Churg, J 

1968 

Yes 

JAMA: Journal of the American Medical Association
ISSN: 0098-7484
EISSN: 1538-3598 

204 

2 

106-112 

English 

5694532 

10.1001/jama.1968.03140150010003 

BCI:BCI19684900095339 

has translation 3699616 [Exposure to asbestos, smoking, and neoplasms. 1967]

Asbestos insulation workers, as a group, have a high risk of dying of bronchogenic carcinoma (about seven or eight times expected). We have observed 370 such workmen from Jan 1, 1963 to April 30, 1967. Our findings indicate that asbestos exposure alone is not the entire explanation. Of 87 noncigarette smokers, none died of bronchogenic carcinoma. Of 283 workmen with a history of regular cigarette smoking, 24 died of bronchogenic carcinoma, although only three were expected to die of this disease. Calculations suggest that asbestos workers who smoke have about 92 times the risk of dying of bronchogenic carcinoma as men who neither work with asbestos nor smoke cigarettes. We conclude that asbestos exposure should be minimized, that asbestos workers who do not smoke should never start, and that those now smoking should stop immediately. 

Abridged Index Medicus; Index Medicus; Peritoneal Diseases -- mortality; Colonic Neoplasms -- mortality; Middle Aged; Environmental Exposure; Stomach Neoplasms -- mortality; Tracheal Neoplasms -- mortality; Pleural Neoplasms -- mortality; Cardiovascular Diseases -- mortality; Rectal Neoplasms -- mortality; Bronchial Neoplasms -- mortality; Asbestosis -- mortality; Carcinoma, Bronchogenic -- etiology; Occupational Diseases; Lung Neoplasms -- etiology; Smoking