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1938040 
Journal Article 
Review 
Neuroimaging of toxic and metabolic disorders 
Arora, A; Neema, M; Stankiewicz, J; Guss, ZD; Guss, JG; Prockop, L; Bakshi, R 
2008 
1 
Seminars in Neurology
ISSN: 0271-8235
EISSN: 1098-9021 
28 
4 
495-510 
English 
18843577 
WOS:000260171100010 
Imaging of the brain, magnetic resonance imaging (MRI) in particular, is a key adjunctive tool in the diagnosis and management of toxic-metabolic disorders such as alcoholism, mitochondrial encephalopathies, disorders of iron or copper metabolism, exposure to carbon monoxide, radiotherapy, immunosuppressive agents, toluene, and recreational drugs. In this article, we review the neuroimaging findings of common toxic and metabolic disorders focusing on the role of conventional MRI. We also consider advanced imaging methods, such as magnetic resonance spectroscopy, diffusion MRI, and positron emission tomography. We hope this article will prove useful to trainees and practitioners in the clinical and imaging fields of the neurosciences. 
Toxin exposure; metabolic disorders; MRI; brain; neurotoxicity