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1993904 
Journal Article 
Gastrointestinal absorption of aluminum from aluminum-containing antacids 
Kaehny, WD; Hegg, AP; Alfrey, AC 
1977 
1 
New England Journal of Medicine
ISSN: 0028-4793
EISSN: 1533-4406 
296 
24 
1389-1390 
English 
859546 
WOS:A1977DJ32700007 
Flameless atomic absorption spectrophotometry was used to measure GI absorption of aluminum from aluminum containing antacids in 13 healthy adult subjects. Subjects ingested 2.2 g of aluminum in divided doses between meals in the form of one of the 4 following compounds: (1) aluminum hydroxide gel; (2) Basaljel (aluminum carbonate gel); (3) Robalate powder (dihydroxyaluminum aminoacetate) and (4) Phosphalgel (aluminum phosphate). Levels of plasma and urinary aluminum rose significantly above control values during aluminum hydroxide, carbonate and aminoacetate administration. Although urinary aluminum excretion rose significantly during aluminum phosphate intake, the cumulative increase was significantly less than that seen during aluminum hydroxide ingestion.