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Citation
Tags
HERO ID
2011449
Reference Type
Journal Article
Subtype
Review
Title
Phenylpropanoid Biosynthesis
Author(s)
Vogt, T
Year
2010
Is Peer Reviewed?
1
Journal
Molecular Plant
ISSN:
1674-2052
EISSN:
1752-9867
Volume
3
Issue
1
Page Numbers
2-20
Language
English
PMID
20035037
DOI
10.1093/mp/ssp106
Web of Science Id
WOS:000273893200002
Abstract
The general phenylpropanoid metabolism generates an enormous array of secondary metabolites based on the few intermediates of the shikimate pathway as the core unit. The resulting hydroxycinnamic acids and esters are amplified in several cascades by a combination of reductases, oxygenases, and transferases to result in an organ and developmentally specific pattern of metabolites, characteristic for each plant species. During the last decade, methodology driven targeted and non-targeted approaches in several plant species have enabled the identification of the participating enzymes of this complex biosynthetic machinery, and revealed numerous genes, enzymes, and metabolites essential for regulation and compartmentation. Considerable success in structural and computational biology, combined with the analytical sensitivity to detect even trace compounds and smallest changes in the metabolite, transcript, or enzyme pattern, has facilitated progress towards a comprehensive view of the plant response to its biotic and abiotic environment. Transgenic approaches have been used to reveal insights into an apparently redundant gene and enzyme pattern required for functional integrity and plasticity of the various phenylpropanoid biosynthetic pathways. Nevertheless, the function and impact of all members of a gene family remain to be completely established. This review aims to give an update on the various facets of the general phenylpropanoid pathway, which is not only restricted to common lignin or flavonoid biosynthesis, but feeds into a variety of other aromatic metabolites like coumarins, phenolic volatiles, or hydrolyzable tannins.
Keywords
Phenylpropanoid; biosynthetic pathway; flavonoid; anthocyanin; tannin; coumarin; volatiles; lignin
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