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2032505 
Book/Book Chapter 
SYNTHESIS OF RHENANITE (beta-NaCaPO(4))-APATITIC CALCIUM PHOSPHATE BIPHASICS FOR SKELETAL REPAIR 
Knotts, RM; Jalota, S; Bhaduri, SB; Tas, AC 
2009 
CERAMIC ENGINEERING AND SCIENCE PROCEEDINGS 
29 
7 
151-164 
WOS:000265018400014 
Biphasic rhenanite (beta-NaCaPO(4))-apatitic calcium phosphate biomaterials for skeletal repair were prepared by using a one-pot, solution-based synthesis procedure at the physiological pH of 7.4, followed by low-temperature (300 degrees to 600 degrees C) calcination in air for 6 hours. Calcination was for the sole purpose of crystallization. An aqueous solution of Ca(NO(3))(2).4H(2)O was rapidly added to a solution of Na(2)HPO(4) and NaHCO(3) at room temperature, followed by immediate filtration of gel-like, poorly-crystallized precursor precipitates from the mother liquors of pH 7.4. Freeze-dried precursors were found to be nanosize with an average particle size of 45 mm and surface area of ca. 125 m(2)/g. Upon calcination in air, precursor powders crystallized into biphasic (60% HA-40% rhenanite) biomaterials, while retaining their submicron particle sizes and high surface areas. Phase-pure rhenanite powders were also synthesized by solid-state reactive firing. Rhenanite is a high solubility sodium calcium phosphate phase. Samples were characterized by XRD, FTIR, SEM, ICP-AES, TG, DTA, DSC, and BET surface area measurements.