Health & Environmental Research Online (HERO)


Print Feedback Export to File
2041902 
Journal Article 
Fucoidans from Brown Seaweeds Sargassum hornery, Eclonia cava, Costaria costata: Structural Characteristics and Anticancer Activity 
Ermakova, S; Sokolova, R; Kim, SMin; Um, BHun; Isakov, V; Zvyagintseva, T 
2011 
Yes 
Applied Biochemistry and Biotechnology
ISSN: 0273-2289
EISSN: 1559-0291 
164 
6 
841-850 
English 
21302149 
WOS:000291218200011 
Fucoidans were isolated by water extraction and ion-exchange chromatography from brown algae Eclonia cava, Sargassum hornery, and Costaria costata collected near of Korean coasts. The structures of fucoidans were investigated. Fucoidan from E. cava was mixture of sulfated rhamnogalactofucan and galactofucan. Fucoidan from C. costata was a sulfated galactofucan. Fucoidan isolated from S. hornery was separated into three fractions: a homofucan sulfate, a homofucan but without sulfate groups, and a sulfated rhamnofucan. The results clearly showed that fucoidans play an inhibitory role in colony formation in human melanoma and colon cancer cells and may be effective antitumor agents. 
Fucoidans; Structure; Anticancer activity