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2044002 
Journal Article 
Studies on novel radiopaque methyl methacrylate: glycidyl methacrylate based polymer for biomedical applications 
Dawlee, S; Jayakrishnan, A; Jayabalan, M 
2009 
Yes 
Journal of Materials Science: Materials in Medicine
ISSN: 0957-4530
EISSN: 1573-4838 
20 
243-250 
English 
18668209 
WOS:000272911800033 
A new class of radiopaque copolymer using methyl methacrylate (MMA) and glycidyl methacrylate (GMA) monomers was synthesized and characterized. The copolymer was made radiopaque by the epoxide ring opening of GMA using the catalyst o-phenylenediamine and the subsequent covalent attachment of elemental iodine. The copolymer was characterized by Fourier transform infrared (FTIR) spectra, energy dispersive X-ray analysis using environmental scanning electron microscope (EDAX), thermogravimetric analysis (TGA), and differential scanning calorimetry (DSC). X-ray visibility of the copolymer was checked by X-radiography. Blood compatibility and cytotoxicity of the newly synthesized copolymer were also evaluated. The iodinated copolymer was thermally stable, blood compatible, non-cytotoxic, and highly radiopaque. The presence of bulky iodine group created a new copolymer with modified properties for potential use in biomedical applications.