Health & Environmental Research Online (HERO)


Print Feedback Export to File
2057199 
Journal Article 
ASSESSMENT OF LAMINATES OF PLASTICS, CELLULOSE AND ALUMINUM AS UNIT DOSE PACKAGING MATERIALS WITH ASPIRIN TABLETS AS A MODEL 
Murray, JB; Beardon, PHG 
1978 
Yes 
Journal of Clinical Pharmacology
ISSN: 0091-2700
EISSN: 1552-4604 
IPA/79/356043 
3 
4 
229-234 
eng 
WOS:A1978FY30800003 
IPA COPYRIGHT: ASHP The effects of temperature and relative humidity on laminates used for packaging unit dose forms were investigated. Aspirin tablets were used as a model and their degradation determined by a spectrofluorimetric assay. The laminates were found to be suitable for use under conditions of 25DGC and 75% relative humidity but unsuitable under conditions of 38DGC and 90% relative humidity. It is therefore recommended that each packaging material be tested with the particular tablet or capsule before large scale packaging is begun.