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HERO ID
2061997
Reference Type
Journal Article
Title
ALUMINUM OVERLOAD IN RENAL-FAILURE PATIENTS AND ITS CLEARANCE FROM TISSUES AFTER KIDNEY-TRANSPLANTATION
Author(s)
Fernandez, MD; Wrobel, K; Defrancisco, ALM; Sanzmedel, A
Year
1994
Is Peer Reviewed?
1
Journal
Trace Elements and Electrolytes
ISSN:
0946-2104
Report Number
BIOSIS/95/00041
Volume
11
Issue
4
Page Numbers
192-198
Language
eng
Web of Science Id
WOS:A1994PN40300008
Abstract
BIOSIS COPYRIGHT: BIOL ABS. Aluminum levels in serum, bone and muscle samples have been evaluated using electrothermal atomic absorption spectrometry technique (ETA-AAS) and the values compared for control (non-uremic) subjects and renal failure patients undergoing regular dialysis treatment. As expected, elevated levels of aluminum in serum (63.8 | 34.3 mug/l) and in bone (29.1 | 16.9 mug/g) were observed in renal failure patients as compared with the corresponding average levels found in control population (9.0 | 1.1 mug/l, 7.1 | 0.4 mug/g respectively). No significative changes in muscle aluminum content were observed between the two groups of subjects under study: 5.9 | 0.5 mug/g for renal failure patients and 5.8 | 2.8 mug/g for the control samples. It appears that only bone aluminum levels correlated with the total amount of aluminum hydroxide ingested (r = 0.5607, p 0.05) by uremic patients to balance their Pa ratio. The effect of kidney transplantation on serum and urine aluminum cont
Keywords
ALUMINUM; SERUM; URINE; BONE; MUSCLE; KIDNEY TRANSPLANTATION; ELECTROTHERMAL ATOMIC ABSORPTION SPECTROMETRY
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