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2064448 
Technical Report 
Soya protein complexes as gastric antacids 
Nema, RK; Jain, CP; Kohli, DV; Rana, AC 
1996 
IPA/98/1153133 
Nat 
REF 13 
22-25 
eng 
IPA COPYRIGHT: ASHP Soya protein isolated from Glycine max (soybean) seeds complexed with different metals like calcium, magnesium, and aluminum (aluminium) were prepared and evaluated in comparison with aluminum hydroxide (aluminium hydroxide) gel for their antacid activity in vitro. Among the various prepared complexes, the calcium complex revealed good neutralizing capacity, rapid onset of action, and prolonged buffering power, while aluminum complex had moderate acid consuming capacity and buffering capacity. The magnesium complex was observed to have very little buffering capacity. In studies using combinations, complex with magnesium oxide (2:1) showed good buffering capacity and rapid action, while the combination with magnesium trisilicate exhibited moderate buffering capacity. The combination with calcium phosphate tribasic (calcium phosphate), however, showed low buffering capacity.