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2065499 
Technical Report 
Bioavailability of beta-acetyldigoxin alone and combined with aluminum hydroxide and magnesium hydroxide (Alucol) 
Bonelli, J; Hruby, K; Magometschnigg, D; Hitzenberger, G; Kaik, G 
1977 
IPA/78/284170 
J 
REF 8 
337-339 
eng 
IPA COPYRIGHT: ASHP The bioavailability of beta-acetyldigoxin (Novodigal) tablets alone and with the antacid tablet Alucol (aluminum hydroxide-magnesium hydroxide) was compared in 6 healthy male volunteers. Statistical analysis of the areas under the curve for both regimens showed no differences. It was concluded that the absorption of beta-acetyldigoxin is not impaired by the concomitant administration of antacid, unlike other studies that have shown that the absorption of digoxin is impaired when combined with antacid.