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2066191 
Journal Article 
Infrared characterization of human sweat glands inhibited with aluminum chlorohydrate 
Strassburger, J; Coble, DW 
1987 
0 
Journal of the Society of Cosmetic Chemists
ISSN: 0037-9832 
IPA/88/778133 
Soc 
REF 28 
eng 
IPA COPYRIGHT: ASHP The mechanism of the antiperspirant action of aluminum chlorohydrate (I) was demonstrated by the infrared spectrometric characterization of poral occlusions in the sweat glands obtained from punch biopsies of the volar forearm of 2 men following overnight treatment with an occlusive patch of 20% I solution. Good evidence was found in the plugs of the formation of a complex between I and keratin in the stratum corneum. In vitro treatment of axillary stratum corneum samples with I solution was used to show the I-protein binding sites and aid in characterizing the in vivo plug spectra.