Health & Environmental Research Online (HERO)


Print Feedback Export to File
2143315 
Journal Article 
A transplantable erythroblastic stem-cell leukemia 
Wise, WC 
1974 
Yes 
Journal of the National Cancer Institute
ISSN: 0027-8874
EISSN: 1460-2105 
HEEP/74/08121 
52 
2 
611-612 
English 
HEEP COPYRIGHT: BIOL ABS. The methods for maintaining an erythroblastic leukemia (EBL) by transplantation of erythroblastic leukemia cells from the liver of an animal with a 7,8,12-trimethylbenz(a)anthracene(TMBA)-induced leukemia into 1-5 day old rat pups were presented. The transplanted leukemia was rapidly induced (less than 18 days) and had a greater than 98% transmission rate. These EBL cells should become a useful system for studies of cellular maturation and neoplastic transformation.