Health & Environmental Research Online (HERO)


Print Feedback Export to File
2143553 
Technical Report 
Metabolism of complex carbohydrates of rabbit skin during treatment with 7, 12-dimethylbenz (a)anthracence 
Prodi, G; Ferreri, AM; Rocchi, P; Grilli, S 
1974 
1 
Zeitschrift für Krebsforschung und klinische Onkologie / Cancer research and clinical oncology
ISSN: 0084-5353 
Springer-Verlag 
HEEP/75/00471* 
81 
2 
161-168 
English 
HEEP COPYRIGHT: BIOL ABS. The metabolism of mucopolysaccharides (MPS) and glycoproteins in rabbit skin was studied after painting with 7,12-dimethylbenz(a)anthracene (DMBA). The synthesis and turnover of MPS increased progressively in the early phases of treatment and remained at high values for the duration of treatment. Sialic acid-containing glycoproteins of fractions soluble and insoluble in saline had variations similar to those of MPS. The data are related to the role attributed to the dermal changes during skin carcinogenesis.