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21503 
Journal Article 
Indirect health effects of relative humidity in indoor environments 
Arundel, AV; Sterling, EM; Biggin, JH; Sterling, TD 
1986 
Yes 
Environmental Health Perspectives
ISSN: 0091-6765
EISSN: 1552-9924 
NIOSH/00168197 
65 
351-361 
English 
A review of the health effects of relative humidity in indoor environments suggests that relative humidity can affect the incidence of respiratory infections and allergies. Experimental studies on airborne-transmitted infectious bacteria and viruses have shown that the survival or infectivity of these organisms is minimized by exposure to relative humidities between 40 and 70%. Nine epidemiological studies examined the relationship between the number of respiratory infections or absenteeism and the relative humidity of the office, residence, or school. The incidence of absenteeism or respiratory infections was found to be lower among people working or living in environments with mid-range versus low or high relative humidities. The indoor size of allergenic mite and fungal populations is directly dependent upon the relative humidity. Mite populations are minimized when the relative humidity is below 50% and reach a maximum size at 80% relative humidity. Most species of fungi cannot grow unless the relative humidity exceeds 60%. Relative humidity also affects the rate of offgassing of formaldehyde from indoor building materials, the rate of formation of acids and salts from sulfur and nitrogen dioxide, and the rate of formation of ozone. The influence of relative humidity on the abundance of allergens, pathogens, and noxious chemicals suggests that indoor relative humidity levels should be considered as a factor of indoor air quality. The majority of adverse health effects caused by relative humidity would be minimized by maintaining indoor levels between 40 and 60%. This would require humidification during winter in areas with cold winter climates. Humidification should preferably use evaporative or steam humidifiers, as cool mist humidifiers can disseminate aerosols contaminated with allergens. 
DCN-154586; Workplace studies; Viral infections; Viral diseases; Skin irritants; Skin disorders; Respiratory irritants; Allergic reactions; Allergic disorders; Eye irritants; Climatic factors; Environmental engineering 
• Formaldehyde [archived]
     Immune Section
          Reviews and reports
     Human Respiratory Pathology
          Found
     Inflammation/Reactive Oxygen Species
          PubMed
          Toxline
          Screened by Title/Abstract
               Not Primary Study: Review, Commentary, Abstract, Policy, Current Practice, Workplace Assessment
     Retroactive RIS import
          2013
               HERO Formaldehyde Immune Section 20Mar2013
               Respiratory Pathology Pubmed WOS Toxline
                    Not About Formaldehyde
          2014
               HERO_Formaldehyde_InflammationReactiveOxygenSpecies_pid_31_uid_5713Sorting091214
               HERO_Formaldehyde_InflammationReactiveOxygenSpecies_pid_31_uid_5713
                    Screened (Title/Abstract)
                         Not Primary Study: Review, Commentary, Abstract, Policy, Current Practice, Workplace Assessment, etc
               Immune_HERO_allyr
               Respiratory Pathology Pubmed_WOS_Toxline_090414
                    Not About Formaldehyde
• IRIS Formaldehyde (Inhalation) [Final 2024]
     Literature Indexing
          PubMed
          Toxline, TSCATS, DART
     Literature Identification
          Respiratory Tract Pathology in Humans
               Excluded
          Immune-Mediated Conditions in Humans, Including Asthma and Allergy
               Supplemental or not primary research
          Inflammation and Immune-Related Mechanistic Studies
               Supplemental or not primary research