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HERO ID
2236378
Reference Type
Journal Article
Subtype
Review
Title
Allergens of weed pollen: An overview on recombinant and natural molecules
Author(s)
Gadermaier, G; Hauser, M; Ferreira, F
Year
2014
Is Peer Reviewed?
1
Journal
Methods
ISSN:
1046-2023
EISSN:
1095-9130
Volume
66
Issue
1
Page Numbers
55-66
Language
English
PMID
23806644
DOI
10.1016/j.ymeth.2013.06.014
Abstract
Weeds represent a botanically unrelated group of plants that usually lack commercial or aesthetical value. Pollen of allergenic weeds are able to trigger type I reactions in allergic patients and can be found in the plant families of Asteraceae, Amaranthaceae, Plantaginaceae, Urticaceae, and Euphorbiaceae. To date, 34 weed pollen allergens are listed in the IUIS allergen nomenclature database, which were physicochemically and immunologically characterized to varying degrees. Relevant allergens of weeds belong to the pectate lyase family, defensin-like family, Ole e 1-like family, non-specific lipid transfer protein 1 family and the pan-allergens profilin and polcalcins. This review provides an overview on weed pollen allergens primarily focusing on the molecular level. In particular, the characteristics and properties of purified recombinant allergens and hypoallergenic derivatives are described and their potential use in diagnosis and therapy of weed pollen allergy is discussed.
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