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2250408 
Journal Article 
Loss of nitroglycerin from intravenous infusion sets 
Cossum, PA; Galbraith, AJ; Roberts, MS; Boyd, GW 
1978 
1 
The Lancet
ISSN: 0140-6736
EISSN: 1474-547X 
IPA/79/322119 
VOL 2 ISS Aug 12 1978 
REF 7 
349-350 
eng 
IPA COPYRIGHT: ASHP The adsorption of nitroglycerin (I) by plastic administration sets with a burette (Buretrol) is reported. A stock solution of 5% I in ethyl alcohol was diluted in 5% dextrose solution to give a 0.01% solution which was placed in a 500 ml infusion bottle to which standard plastic sets were connected. I concentration decreased rapidly within the first hr at all flow rates used, but with faster flow rates, a subsequent small increase occurred before a steady state fraction was reached. For the fastest flow rate, this level was 70% of the original concentration. Very little I was lost when 0.01% solution was delivered from a glass syringe through a short length of high density polyethylene tubing. Less than 1% of I was lost on storage in all glass containers for 24 hr.