Health & Environmental Research Online (HERO)


Print Feedback Export to File
2250597 
Journal Article 
Epinephrine for treatment of anaphylactic shock 
Barach, EM; Nowak, RM; Lee, TG; Tomlanovich, MC 
1984 
Yes 
JAMA: Journal of the American Medical Association
ISSN: 0098-7484
EISSN: 1538-3598 
IPA/85/610039 
VOL 251 ISS Apr 27 1984 
REF 45 
eng 
IPA COPYRIGHT: ASHP Acute cardiotoxicity and myocardial infarction occurring 30 days after treatment in a 34-yr-old patient who was treated for anaphylaxis with 2 doses of a one to 1000 dilution of epinephrine (I), 0.3 mg SC and 0.5 mg IV, were reported. The patient had also received diphenhydramine hydrochloride. The acute toxic effects were treated with morphine sulfate, 2 mg IV, and nitroglycerin, 0.4 mg sublingually. A review of the mechanism of anaphylaxis, the mechanism of action of I and recommendations for the use of I in the therapy of anaphylaxis was included.