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2251008 
Journal Article 
Hypertensive crisis after discontinuation of angiotensin-converting enzyme inhibitor 
Mcalister, FA; Lewanczuk, R 
1994 
1 
The Lancet
ISSN: 0140-6736
EISSN: 1474-547X 
IPA/95/1074066 
VOL 344 ISS Nov 26 1994 
REF 2 
eng 
IPA COPYRIGHT: ASHP A case is described in which a 52-yr-old man experienced a hypertensive crisis after abrupt discontinuation of 30 mg/day lisinopril. Treatment with 10 mg intravenous (IV) metoprolol, 70 mcg/min nitroglycerin, and 9 mg morphine did not improve his blood pressure. An IV dose of 0.625 mg enalaprilat was then given with good effect. The patient's blood pressure decreased to 180/94 mm Hg. With control of his blood pressure the patient was given aspirin, streptokinase, and IV heparin. Blood pressure was controlled with 20 mg/day lisinopril and 200 mg/day metoprolol.