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HERO ID
2261994
Reference Type
Journal Article
Title
Synthesis, Characterization and Ct-DNA Interaction Study of Two Vanadium Complexes
Author(s)
Zhou Yinzhuang; Feng Jingnan; Yue Lei; Tu Shujie; Zhu Huiju
Year
2009
Is Peer Reviewed?
Yes
Journal
Huaxue Xuebao / Acta Chemica Sinica
ISSN:
0567-7351
Volume
67
Issue
12
Page Numbers
1297-1302
Web of Science Id
WOS:000267849800004
Abstract
Two vanadium complexes with o-vanillin derivatives, [VO(2)(C(10)H(11)NO(3)](HOCH(2)CH(2)NH(3)) (1) and VO(C(8)H(8)NO(3))(2) (2), were synthesized and characterized by FT-IR and single crystal X-ray diffraction analysis. The interaction of the two complexes with calf thymus-DNA (Ct-DNA) has been investigated by UV-Vis absorption spectroscopy, fluorescence spectroscopy, cyclic voltammetry and viscosity measurements. The results indicated that the complex 1 interacted with Ct-DNA in a non-intercalative mode, while complex 2 might be bonded to Ct-DNA through an intercalative mode.
Keywords
vanadium; o-vanillin; complex; intercalation interaction; calf thymus DNA
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