US EPA

2271226 

Journal Article 

Synthesis, Crystal Structure and DNA-Binding of Lanthanum Complex with Schiff Base Derived from o-Vanillin and p-Toluidine 

Chen, XJu; Hu, W; Qin, Yi; Zhao, G 

2013 

Yes 

Asian Journal of Chemistry
ISSN: 0970-7077
EISSN: 0975-427X 

25 

12 

6615-6618 

WOS:000325088800029 

https://asianpubs.org/index.php/ajchem/article/view/25_13_29
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A new complex [La(NO3)3(C2H5OH)(C15H15NO2)2] was synthesized from lanthanum nitrate and Schiff base (C15H15NO2, derived form o-vanillin and p-toluidine) by refluxing in ethanol. It's crystal structure was determined by single crystal X-ray diffraction method. The complex is crystallize in triclinic, space group P-1, with a = 0.79851(3) nm, b = 1.47473(5) nm, c = 1.63872(6) nm, a = 73.546(2)degrees, b = 86.769(2)degrees, gamma = 79.767(2)degrees, V = 1.82123(1) nm(3), Z = 2, M-r = 852.56, F(000) = 1862, Dc = 1.555 g cm(-3), mu(M0K alpha) = 1.056 mm(-1). It turned out that six oxygen atoms from three nirtate anions, one oxygen atom in ethanol and two phenolate oxygen atoms from two Schiff base ligands coordinate to La(III), forming a 9-coordination distorted monocapped square prism geometry. In addition, DNA-binding of the complex was studied by EtBr fluoescent probe and the results show that the complex interact with DNA by intercalative mode. CCDC: 878971. 

Schiff base; o-Vanillin; p-Toluidine; Lanthanum complex; Crystal structure; DNA-binding