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Citation
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HERO ID
2273173
Reference Type
Journal Article
Title
Measuring Protein Synthesis With SUnSET: A Valid Alternative to Traditional Techniques?
Author(s)
Goodman, CA; Hornberger, TA
Year
2013
Is Peer Reviewed?
Yes
Journal
Exercise and sport sciences reviews
ISSN:
0091-6331
EISSN:
1538-3008
Volume
41
Issue
2
Page Numbers
107-115
PMID
23089927
DOI
10.1097/JES.0b013e3182798a95
Web of Science Id
WOS:000316733100007
Abstract
GOODMAN, C. A. and T. A. HORNBERGER. Measuring protein synthesis with SUnSET: a valid alternative to traditional techniques? Exerc. Sport Sci. Rev., Vol. 41, No. 2, pp. 107-115, 2013. Protein synthesis rates commonly are measured using isotopic tracers to quantify the incorporation of a labeled amino acid into muscle proteins. Here we provide evidence supporting our hypothesis that the nonisotopic SUnSET technique is a valid and accurate method for the measurement of in vivo changes in protein synthesis at the whole-muscle and single-muscle fiber levels.
Keywords
skeletal muscle; translation; hypertrophy; atrophy; puromycin; muscle fiber type; myosin heavy chain
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