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2292102 
Journal Article 
Structural and bioactive studies of terpenes and cyclopeptides from the Genus Rubia 
Xu, Kuo; Wang, P; Yuan, Bin; Cheng, Y; Li, Q; Lei, H 
2013 
Yes 
Chemistry Central Journal
ISSN: 1752-153X 
7 
23642144 
WOS:000321140700001 
Genus Rubia fell into about 70 species distributed widely around the world, a total of 36 species and 2 varieties were reported from China. The extracts and phytochemicals of Rubia plants had drawn considerable attention due to their potent bioactivities. As the two major ingredients from these plants, pentacyclic triterpenes and cyclopeptides were becoming a hot topic over the past twenty years for their remarkable anticancer, antioxidant and other effects. This paper compiled all 65 terpenes and 44 cyclopeptides with their distributions, physiological activities and melting points (or optical rotations) as reported in 85 references; besides, structure-activity relationships of these derivatives were briefly discussed. The information involved in this paper was expected to be meaningful for the further studies of the Genus Rubia. 
Genus Rubia; Phytochemicals; Terpenes; Cyclopeptides; Bioactivities