Health & Environmental Research Online (HERO)


Print Feedback Export to File
2299877 
Technical Report 
A comparative assessment of toxic and mutagenic properties of certain organic compounds of tin 
Belyaeva, NN; Bystrova, TA; Revazova YuA; Arkhangelsky, VI 
1976 
PESTAB/77/0409 
Sanit 
5 
10-14; 1976 
rus 
PESTAB. Three organic tin compounds (bistributyltin oxide, monobutyltin oxide, monobutyltin trilaurate, tin dibutyl difluoroacetate) were tested for mutagenic activity. Fruit flies and mammalian bone marrow cells were studied after exposure to the compounds. The percentages of abnormal mammalian bone marrow anatelophases were 11.7% for bistributyltin oxide, 13.2% for monobutyltin trilaurate, and 6.2% for tin dibutyl ditrifluoroacetate, compared to 2.3% for controls. Chromatid gaps and unicentric fragments were the most prominent abnormalities.