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2301238 
Technical Report 
Synthesis and study of the anesthetizing action of some dialkylaminoacetic acid anilides 
Vartanyan, RS; Martirosyan, VO; Viasenko, EV; Durgaryan, LK; Azlivyan, AS 
1982 
IPA/83/524084 
Chem 
USSR 
185-190 
eng 
IPA COPYRIGHT: ASHP Three phenylimines, 3 phenylamines, 3-chloroacetic acid anilides and 15 dialkylaminoacetic acid anilides were synthesized and the latter were tested for anesthetic activity in in vitro and animal studies. One compound showed the greatest effects, both in local anesthetic activity in isolated frog nerves and infiltration anesthesia in guinea pigs. Weak activity for a number of compounds was observed in surface anesthesia of intact rabbit corneas.