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2611834 
Journal Article 
Magnetic Nanotechnology for Biodetection 
Han, ShuJen; Wang, S 
2010 
1 
The Association for Laboratory Automation. Journal
ISSN: 1535-5535 
15 
2 
93-98 
WOS:000285163500004 
A highly sensitive biodetection technology using nanomagnetic sensors and magnetic nanoparticles (NPs) was developed. Absorption of magnetic NPs by the hybridized DNA alters the sensor resistance and generated electrical signals that can be directly measured with the off-die or on-die circuitry. Assays with DNA concentration down to sub-10 pM with a dynamic range of three orders of magnitude were demonstrated. The proposed biochip can be applied to other bioreaction detections, for example, protein assay, through different surface modifications. (JALA 2010; 15:93-8) 
GMR sensor; magnetic nanoparticle; magnetic biosensor