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2674131 
Journal Article 
Successful Treatment of Epilepsy by Resection of Periventricular Nodular Heterotopia 
Agari, T; Mihara, T; Baba, K; Kobayashi, K; Usui, N; Terada, K; Nakamura, F; Matsuda, K; Date, I 
2012 
Yes 
Acta Medica Okayama
ISSN: 0386-300X 
66 
6 
487-492 
23254583 
WOS:000312966100008 
We report on a case of successful surgical treatment of drug-resistant epilepsy associated with a solitary lesion of periventricular nodular heterotopia (PNH). In the reported patient, intracranial ictal electroencephalography disclosed that seizures did not originate from the heterotopic nodules. However, the seizures were completely suppressed by lesionectomy of PNH alone. Epileptogenesis associated with PM-I likely involves a very complex network between PNH and the surrounding cortex, and the disruption of this network may be an effective means of curing intractable, PNH-associated epilepsy. 
periventricular nodular heterotopia; epilepsy; surgery; ictal electroencephalography