Nitrite bioaccumulation in Salmo gairdneri and hematological consequences | Health & Environmental Research Online (HERO)

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Citation
Tags

HERO ID

2723158

Reference Type

Journal Article

Title

Nitrite bioaccumulation in Salmo gairdneri and hematological consequences

Author(s)

Margiocco, C; Arillo, A; Mensi, P; Schenone, G

Year

1983

Is Peer Reviewed?

Yes

Journal

Aquatic Toxicology
ISSN: 0166-445X
EISSN: 1879-1514

Report Number

HEEP/84/00272

Volume

AMST

Issue

AMST

Page Numbers

261-270

Language

English

Abstract

HEEP COPYRIGHT: BIOL ABS. S. gairdneri exposed to 450 mug/l (NO2-N) environmental nitrite, and examined after various periods of treatment, did not possess methemoglobin (met Hb) levels correlatable to their physiological conditions, or proportional to their hematic nitrite concentration. Functional Hb content (total Hb minus metHb) was connected to a physiological state only in the early stages of intoxication. Nitrite accumulated in blood and tissues of fish to a high extent (up to 60-fold the environmental concentration) against increasing concentration gradients. The nitrite concentration in blood was linked to exposure time more than to physiological conditions, while in the liver and brain, greater differences existed between apparently unstressed animals and torpid, unreactive trout. Futher evidence was given that death following acute intoxication depended on nitrite toxic action in vital organs rather than on methemoglobinemia.